OXTR Gene (Oxytocin Receptor)
The gene regulating the receptor sensitivity for Oxytocin, the neurochemical responsible for bonding, trust, and the feeling of satisfaction.
Deep Dive
Variants in the OXTR gene can dull the 'satisfaction signal' in the brain. Oxytocin is often called the 'love hormone,' but its role extends far beyond romantic bonding — it regulates social cognition, trust, empathy, stress resilience, and the deep sense of contentment after meaningful connection.
People with lower receptor sensitivity often describe a persistent 'empty feeling' or difficulty feeling connected, even in close relationships. This can drive addictive behaviours — seeking dopamine hits from food, social media, or substances to replace the missing oxytocin fulfilment.
Understanding your OXTR status provides crucial context for mental health and behavioural patterns. Individuals with reduced oxytocin receptor sensitivity may benefit from targeted lifestyle interventions including physical touch, community engagement, meditation practices, and in some cases, specific peptide protocols under clinical supervision.